Fig. 1
From: The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy
Analysis of m6A contents and m6A regulators in GO specimens and controls. a The m6A contents in total RNA was significantly increased in GO specimens (n = 7) compared with controls (n = 5) (*p < 0.05). OD reading at 450 nm. b m6A modification–associated genes were examined by RNA-seq in GO (n = 4) extraocular muscles and controls (n = 4). The values of the statistics analysis are included in the Figs. c Twelve selected m6A modification–associated genes were examined in patients with GO (n = 7) and controls (n = 5) by quantitative PCR and normalized to GAPDH. Student’s t-test was used to assess the differences of each gene between patients in GO and controls. * indicates significant increases of m6A mRNA in GO specimens compared with controls (P < 0.05)