|
Univariate analysis
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Multivariate analysis
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|---|
|
6-month follow-up
| |
PCE
|
PTE
|
PME
|
6-month follow-up
|
PCE
|
PTE
|
PME
|
|
Parameters
| |
Correlation coefficient
|
P value
|
Correlation coefficient
|
P value
|
Correlation coefficient
|
P value
|
Parameters
|
Correlation coefficient
|
P value
|
Correlation coefficient
|
P value
|
Correlation coefficient
|
P value
|
|
Sex
|
Male
|
−1.32 ± 3.01
|
< 0.05
|
−0.48 ± 2.74
|
< 0.05
|
−0.24 ± 1.85
|
0.98
|
Sex (Male vs. Female)
|
−1.99 ± 0.74
|
0.01
|
−2.15 ± 0.72
|
0.003
|
NS
|
0.84
|
|
Female
|
1.13 ± 4.23
|
2.04 ± 4.32
|
−0.25 ± 1.93
|
|
Age
|
≥20
|
−2.00 ± 2.28
|
0.16
|
0.80 ± 1.64
|
0.09
|
−2.67 ± 3.21
|
0.13
|
Age
|
0.19 ± 0.07
|
0.003
|
0.19 ± 0.07
|
0.01
|
NS
|
1.00
|
|
21 ~ 30
|
0.05 ± 4.28
|
1.00 ± 4.30
|
−0.04 ± 1.97
|
|
31 ~ 40
|
0.67 ± 3.83
|
1.30 ± 3.72
|
−0.39 ± 1.54
|
|
≥41
|
3.50 ± 3.42
|
4.88 ± 3.94
|
−0.36 ± 1.66
|
|
Surgical group
|
FS-LASIK
|
1.34 ± 4.21
|
0.23
|
2.09 ± 4.00
|
0.35
|
0.03 ± 1.88
|
0.04
|
Surgical group (SMILE vs. FS-LASIK)
|
NS
|
0.26
|
NS
|
0.36
|
NS
|
0.42
|
|
SMILE
|
0.26 ± 4.21
|
1.23 ± 4.37
|
−0.82 ± 1.82
|
|
Ablation ratioa
|
High-level
|
0.69 ± 4.43
|
0.87
|
1.69 ± 4.43
|
0.7
|
−0.35 ± 1.79
|
0.63
|
Ablation ratio
|
NS
|
0.76
|
NS
|
0.82
|
NS
|
0.90
|
|
Low-level
|
0.55 ± 4.08
|
1.36 ± 4.14
|
−0.16 ± 1.98
|
|
5-year follow-up
| |
PCE
| |
PTE
| |
PME
| |
5-year follow-up
|
PCE
|
PTE
|
PME
|
|
Sex
|
Male
|
1.38 ± 4.97
|
0.6
|
2.07 ± 5.26
|
0.95
|
0.28 ± 2.26
|
0.38
|
Gender (Male vs. Female)
|
NS
|
0.81
|
NS
|
0.90
|
NS
|
0.78
|
|
Female
|
0.76 ± 5.75
|
1.99 ± 6.20
|
−0.15 ± 2.25
|
|
Age
|
≥20
|
2.43 ± 3.55
|
0.23
|
3.57 ± 3.21
|
0.24
|
1.23 ± 1.90
|
< 0.001
|
Age
|
NS
|
0.31
|
NS
|
0.28
|
−0.13 ± 0.04
|
0.001
|
|
21 ~ 30
|
1.46 ± 5.23
|
2.55 ± 5.70
|
0.44 ± 1.99
|
|
31 ~ 40
|
0.13 ± 4.16
|
1.39 ± 4.79
|
−0.59 ± 2.24
|
|
≥41
|
−1.73 ± 10.27
|
−1.00 ± 10.42
|
−2.35 ± 2.38
|
|
Surgical group
|
FS-LASIK
|
1.63 ± 5.83
|
0.18
|
2.74 ± 6.13
|
0.22
|
−0.01 ± 2.21
|
0.83
|
Surgical group (SMILE vs. FS-LASIK)
|
NS
|
0.75
|
NS
|
0.80
|
NS
|
0.88
|
|
SMILE
|
0.30 ± 5.25
|
1.42 ± 5.78
|
−0.01 ± 2.27
|
|
Ablation ratioa
|
High-level
|
2.33 ± 4.68
|
< 0.05
|
3.38 ± 4.88
|
< 0.05
|
0.20 ± 2.03
|
0.25
|
Ablation ratio
|
2.68 ± 1.05
|
0.01
|
2.35 ± 1.17
|
0.04
|
NS
|
0.48
|
|
Low-level
|
−0.56 ± 5.99
|
0.61 ± 6.64
|
−0.28 ± 2.40
|
- aHigh and low-level were divided by median ablation ratio in univariate analysis. Parameters with P value less than 0.1 in any one of follow-ups were entered into a multivariable analysis using generalized estimating equations. SMILE= small incision lenticule extraction; FS-LASIK=femtosecond laser-assisted in situ keratomileusis; PCE=posterior central elevation; PTE=posterior corneal surface at thinnest point; PME=posterior corneal mean elevation; NS=not significant. P values less than 0.05 were considered statistically significant
