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Table 4 Mean ± standard deviation of the main discriminators in the Down syndrome (DS) keratoconus (DS-KC), DS keratoconus suspect (DS-KCS), DS non-ectatic comparison (DS-C), and non-DS normal control (NC) groups of the study

From: Tomography-based definition of keratoconus for Down syndrome patients

Index

DS-KC

(n = 25)

DS-KCS

(n = 46)

DS-C

(n = 154)

NC

(n = 200)

Minimum corneal thickness (μm)

484.12 ± 32.34

492.28 ± 37.57

515.48 ± 30.36

546.9 ± 40.5

Corneal Volume (mm3)

57.45 ± 4.37

55.13 ± 3.35

57.62 ± 3.26

61.19 ± 4.04

Belin Ambrosio display-total deviation

2.98 ± 1.44

2.26 ± 0.66

1.72 ± 1.02

1.20 ± 0.53

Anterior HOA (μm)

1.13 ± 1.00

0.60 ± 0.17

0.55 ± 0.18

0.37 ± 0.09

Posterior vertical coma (μm)

0.15 ± 0.19

0.06 ± 0.04

0.05 ± 0.03

0.02 ± 0.02

Anterior vertical coma (μm)

0.70 ± 0.77

0.29 ± 0.19

0.20 ± 0.13

0.14 ± 0.09

Total HOA (μm)

1.12 ± 0.89

0.62 ± 0.17

0.57 ± 0.19

0.38 ± 0.12

  1. Differences between the four groups were significant by one-way ANOVA and post hoc Scheffe for all indices except aberration indices between DS-KCS and DS-C groups