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Table 4 Prior ROP AI study performance comparison

From: Automated identification of retinopathy of prematurity by image-based deep learning

Reference

Patients (N)

Cases

Images

Labels

Model

Specificity

Sensitivity

Accuracy

Wang et al. [35]

1273

3722

20,795

normal/minor

Id-Net; Gr-Net

99.32% (Id-Net);

96.62% (Id-Net); 88.46% (Gr-Net)

–

ROP/severe ROP

92.31% (Gr-Net)

Brown et al. [19]

898

1762

5511

normal/pre-plus

U-net (Inception-v1)

94% (plus disease)

93% (plus disease); 100% (pre-plus disease)

–

disease/plus disease

94% (pre-plus disease)

Worrall et al. [34]

35

347

1459

normal/plus disease

GoogleNet; Bayesian CNNs

0.983 (per image)

0.825 (per image)

–

0.954 (per exam)

0.947 (per exam)

Campbell et al. [37]

–

–

77

normal/pre-plus

i-ROP

–

–

95%

disease/plus disease

Hu et al. [38]

720

–

3017

normal/mild

Inception-v2; VGG-16; ResNet-50

–

–

0.970 (normal and ROP);

ROP/severe ROP

0.840 (mild and severe)

  1. ROP = retinopathy of prematurity; GoogleNet = google inception net; CNN = convolutional neural network; VGG = visual geometry group; ResNet = residual network