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Fig. 2 | Eye and Vision

Fig. 2

From: MicroRNA-184 negatively regulates corneal epithelial wound healing via targeting CDC25A, CARM1, and LASP1

Fig. 2

Ectopic miR-184 transfection delays corneal epithelial wound healing. a C57BL/6 J mice were injected in the stromal periphery beneath the limbus with miR-184, PEI, and 10% glucose solution. In the fellow eye, the injection contained the negative control (NC). Epithelial scraping was performed 6 h post-injection and epithelial wound areas were observed by staining with sodium fluorescein after 24 h. Wound edges are demarcated in white. b The percentage of wound closure (%) was evaluated by normalizing the healing area to the initial wound area at 0 h (n = 16/group). c RT-qPCR analysis evaluated miR-184 expression level in each murine eye (n = 16/group)

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Eye and Vision

ISSN: 2326-0254