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Fig. 2 | Eye and Vision

Fig. 2

From: Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography

Fig. 2

Worsening and stability of IRMAs after anti-VEGF treatment. The upper row demonstrates foci of IRMAs (arrows) prior to intervention and the lower row demonstrates the same IRMA foci after anti-VEGF injection. Panels (a, b, g & h) represent progression of IRMAs (yellow and green arrows). The surrounding area of non-perfusion has enlarged with loss of previously adjacent capillaries (white arrow heads). IRMAs in this category either developed more branching (green arrows) or a newly formed IRMAs appeared (yellow arrow). Panels (c, d, i & j) represent IRMA obliteration (drop-out), which is an end-stage progression of ischemia leading to massive obliteration of the vascular bed (white arrow heads), which eventually included the IRMAs itself (purple and orange arrows). Panels e, f, k & l demonstrate stable IRMAs (red and light blue arrows) where there is no change in the area of non-perfusion, IRMAs caliber, or branching

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