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Table 1 Excimer laser trabeculostomy: breakdown of current studies

From: Current review of Excimer laser Trabeculostomy

AuthorsType of studyInclusion criteriaELT spotsStudy durationIntervention/comparatorN of eyesPreop IOP (mmHg)Preop meds Postop IOP (mmHg)Postop meds
Randomized control trial
 Babighian et al.Prospective, comparativeMild to moderate POAG82 yearsELT1525 ± 1.92.3 ± 0.717.6 ± 2.20.7 ± 0.8
SLT1523.9 ± 0.92.2 ± 0.719.1 ± 1.80.9 ± 0.8
Prospective case series
 Babighian et al.Prospective nonrandomized trial, comparativePOAG82 yearsELT2124.8 ± 2.02.24 ± 0.616.9 ± 2.10.71 ± 0.8
Drops2121.67 ± 1.621.0 ± 0.5
 Töteberg-Harms et al.Prospective consecutive case seriesOHT or mild to moderate OAG101 yearELT + CE6419.8 ± 5.32.4 ± 1.115.2 ± 4.41.5 ± 1.4
 Berlin et al.aProspective interventional case seriesOAG5–108 yearsELT4622.9 ± 5.41.6 ± 0.716.1 ± 3.41.2 ± 1.2
ELT + CE3725.1 ± 6.11.3 ± 0.714.2 ± 3.11.8 ± 0.8
 Kleineberg et al.aProspective observational study, comparativeMild to moderate OAG101 yearELT + steroids2524.9 ± 2.72.017.0 ± 4.00.4
ELT + NSAID2326.3 ± 2.5 (n = 23)1.7 (n = 23)16.0 ± 3.5 (n = 22)0.6 (n = 22)
ELT + CE4322.2 ± 1.71.412.0 ± 2.80.2
5 yearsELT + steroids2524.9 ± 2.7 (n = 25)2.0 (n = 25)15.0 ± 3.2 (n = 15)0.8 (n = 15)
ELT + NSAID2326.3 ± 2.5 (n = 23)1.7 (n = 23)16.0 ± 2.6 (n = 15)0.9 (n = 15)
ELT + CE4322.2 ± 1.7 (n = 43)1.4 (n = 43)14.0 ± 2.6 (n = 31)0.9 (n = 31)
Retrospective comparative study
 Wilmsmeyer et al.Retrospective case series, comparativeOHT or mild to moderate OAG101 yearELT7524.1 ± 0.7 (n = 69)1.9 ± 0.1 (n = 69)18.8 ± 0.8 (n = 37)1.8 ± 0.2 (n = 37)
ELT + CE6022.4 ± 0.6 (n = 57)1.1 ± 0.2 (n = 57)16.4 ± 0.4 (n = 35)1.2 ± 0.2 (n = 35)
2 yearsELT7524.1 ± 0.7 (n = 69)1.9 ± 0.1 (n = 69)16.8 ± 1.0 (n = 15)1.5 ± 0.3 (n = 15)
ELT + CE6022.4 ± 0.6 (n = 57)1.1 ± 0.2 (n = 57)12.8 ± 1.5 (n = 4)1.8 ± 0.9 (n = 4)
 Töteberg-Harms et al.Retrospective interventional case series, comparativeMild to moderate OAG104 yearsELT + CE5119.0 ± 9.0 (n = 51) median ± IQR2 ± 1 (n = 51)14.0 ± 5.5 (n = 50)1 ± 2 (n = 50)
Trab+CE6222.8 ± 6.3 (n = 62)2 ± 1 (n = 62)14.0 ± 3.5 (n = 58)0 (n = 58)
 Jozic et al.Retrospective interventional case series, comparativeOAG101 yearCE3816.7 ± 3.81.1 ± 0.615.2 ± 3.11.0 ± 0.7
ELT + CE10517.8 ± 4.31.4 ± 0.713.2 ± 2.30.5 ± 0.8
ELT + Trabectome10219.3 ± 4.61.3 ± 0.813.8 ± 2.20.5 ± 0.7
Retrospective case series
 Töteberg-Harms et al.Retrospective case seriesOHT or mild to moderate OAG101 yearELT + CE2825.3 ± 2.92.3 ± 1.316.5 ± 5.01.5 ± 1.4
 Moreno Valladares et al.Retrospective interventional case seriesMild to moderate OAG106 monthsELT or ELT + CE2721.21.817.80.7
  1. aUnpublished studies
  2. preop= preoperative; IOP= intraocular pressure; postop= postoperative; SD= standard deviation; IQR= interquartile range; POAG= primary open-angle glaucoma; OAG= open-angle glaucoma; OHT= ocular hypertension; NSAID= non-steroidal anti-inflammatory drug; ELT= Excimer laser trabeculostomy; CE= cataract Extraction; Trab= trabeculectomy.