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Table 2 Clinical results of the implantation of ICRS using the ANN and the manufacturer’s nomogram

From: Artificial neural network to guide intracorneal ring segments implantation for keratoconus treatment: a pilot study

 VariablesPre-opPost-opP value
ANN groupUDVA [Decimal value (LogMAR)]0.17 ± 0.14
(0.77)
0.37 ± 0.21
(0.43)
p = 0.001
CDVA [Decimal value (LogMAR)]0.60 ± 0.23
(0.22)
0.73 ± 0.21
(0.14)
p < 0.005
SE (D)−3.89 ± 3.66−2.58 ± 2.40p < 0.05
Sim-K1 (D)45.58 ± 4.0543.71 ± 4.27p < 0.001
Sim-K2 (D)49.80 ± 3.9647.13 ± 4.56p = 0.001
Sim-K Avg (D)47.56 ± 3.8445.33 ± 4.32p < 0.001
CCT (μm)474.20 ± 40.93472.90 ± 48.44p > 0.05
ThkMin (μm)457.95 ± 43.75442.05 ± 49.05p < 0.01
Corneal volume (mm3)54.30 ± 2.9255.17 ± 3.25p < 0.05
Total aberrations (μm)5.36 ± 2.574.91 ± 2.76p > 0.05
High Order aberrations (μm)3.69 ± 2.093.34 ± 1.93p > 0.05
Astigmatism aberrations (μm)3.62 ± 2.373.47 ± 2.31p > 0.05
Coma-like aberrations (μm)3.56 ± 2.082.71 ± 1.48p < 0.05
Spherical-like aberrations (μm)0.93 ± 0.351.84 ± 1.41p < 0.005
Nomogram groupUDVA [Decimal value (LogMAR)]0.12 ± 0.11
(0.92)
0.36 ± 0.23
(0.44)
p < 0.001
CDVA [Decimal value (LogMAR)]0.54 ± 0.19
(0.27)
0.62 ± 0.19
(0.21)
p < 0.01
SE (D)−4.96 ± 4.16−1.80 ± 2.48p = 0.001
Sim-K1 (D)44.37 ± 4.7943.15 ± 4.29p > 0.05
Sim-K2 (D)48.95 ± 5.4845.98 ± 4.44p < 0.001
Sim-K Avg (D)46.50 ± 4.8444.98 ± 5.32p < 0.005
CCT (μm)457 ± 55.50453.45 ± 57.25p > 0.05
ThkMin (μm)443.55 ± 54.72431.95 ± 56.43p < 0.05
Corneal volume (mm3)53.40 ± 3.4753.46 ± 4.43p > 0.05
Total aberrations (μm)5.66 ± 3.544.39 ± 2.76p < 0.05
High Order aberrations (μm)3.30 ± 2.183.42 ± 2.23p > 0.05
Astigmatism aberrations (μm)4.16 ± 3.432.36 ± 2.18p < 0.005
Coma-like aberrations (μm)3.10 ± 2.132.93 ± 2.20p > 0.05
Spherical-like aberrations (μm)1.05 ± 0.671.58 ± 0.89p < 0.005
  1. Preoperatively, the ANN group and the nomogram group do not differ significantly in any of the parameters evaluated (p > 0.05). Postoperatively, the ANN group and the nomogram group differed significantly in CDVA (p < 0.05). Visual acuity is expressed in decimal value and the corresponding LogMAR value is reported in brackets