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Table 4 ROC Curve Analysis of RCDs in the Retinal Capillary Layers and GCC Thickness in TAO Patients with DON

From: Reduced macular inner retinal thickness and microvascular density in the early stage of patients with dysthyroid optic neuropathy

 

GCC + SRCL

GCC + DRCL

 

Cut off

   

Cut off

  

Regions

AUC

GCC (μm)

RCD (%)

Sensitivity (%)

Specificity (%)

AUC

GCC (μm)

RCD (%)

Sensitivity (%)

Specificity (%)

TAZ-C6 Total

0.85

83.2

64.6

79

84

0.86

83.2

79.5

89

66

S-C6

0.86

79.3

66.9

82

82

0.89

86.2

79.5

89

76

T-C6

0.83

92.8

60.2

74

89

0.84

95.4

68.6

66

89

I-C6

0.83

107.8

61.0

82

76

0.86

124.8

66.4

79

79

N-C6

0.85

95.7

61.0

87

76

0.88

80.7

78.6

87

76

  1. RCD = retinal capillary density; GCC = ganglion cell complex; TAO = thyroid-associated ophthalmopathy; DON = dysthyroid optic neuropathy; SRCL = superficial retinal capillary layer; DRCL = deep retinal capillary layer; AUC = areas under the ROC curve; TAZ = total annular zone; S = superior sector; T = temporal sector; I = inferior sector; N = nasal sector