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Table 1 Demographic characteristics of all subjects

From: Reduced macular inner retinal thickness and microvascular density in the early stage of patients with dysthyroid optic neuropathy

ParametersControl (n = 38)Non-DON (n = 23)DON (n = 21)P value
Eyes383638
Age (years)45.2 ± 10.841.9 ± 11.747.6 ± 6.50.174*
Sex, Male/Female19/1912/1111/100.979†
Spherical Equivalent (D)−0.12 ± 0.95−0.22 ± 0.66−0.32 ± 0.630.521*
Intraocular Pressure (mmHg)14.4 ± 2.316.1 ± 3.219.0 ± 6.9<  0.001*
Axial Length (mm)23.5 ± 0.923.3 ± 1.023.3 ± 0.80.520*
Best Corrected Visual Acuity (logMAR)0.00 ± 0.010.00 ± 0.010.15 ± 0.370.005*
Exophthalmometry (mm)17.94 ± 1.9018.58 ± 2.380.228‡
Mean Defect of Visual Field (dB)−0.29 ± 0.54−6.79 ± 3.91<  0.001
Clinical Activity ScoringNA1.08 ± 1.181.73 ± 1.120.019
Duration of Graves’ Disease (yrs)NA4.78 ± 7.033.20 ± 3.440.356‡
History of smoking4/237/210.192†
Free Triiodothyronine (pg/ml)7.13 ± 6.416.25 ± 4.760.192‡
Free Thyroxine (ng/dl)3.41 ± 3.153.61 ± 5.510.389‡
Thyroid-Stimulating Hormone (μIU/ml)7.21 ± 19.011.01 ± 1.370.023
  1. Values for continuous variables are mean ± standard deviation for all subjects in each group. Control = control eyes; Non-DON = TAO patients without DON; DON = TAO patients with DON; DON = dysthyroid optic neuropathy; TAO = thyroid-associated ophthalmopathy; – = not performed; NA = not applicable. Bold P-value represents < 0.05
  2. * ANOVA. † x2 test. ‡ t-test