Table 4 Logistic regression analysis for the assessment of AMD associated genes with KC in males
From: Do age-related macular degeneration genes show association with keratoconus?
| Â | Without age adjustment | Adjusting for age | ||||
|---|---|---|---|---|---|---|
CHR | SNP | Minor Allele Name | Odds Ratio (95% CI) | P | Odds Ratio (95% CI) | P |
22 | rs5749482 | C | 2.29 (1.41–3.71) | 7.7 × 10−4 | 1.76 (1.01–3.08) | 4.8 × 10−2 |
3 | rs6795735 | T | 1.60 (1.15–2.23) | 5.4 × 10− 3 | 1.36 (0.93–1.99) | 1.1 × 10− 1 |
6 | rs943080 | C | 0.68 (0.50–0.94) | 1.9 × 10−2 | 0.75 (0.52–1.09) | 1.4 × 10− 1 |
13 | rs9542236 | C | 0.72 (0.52–1.00) | 4.8 × 10−2 | 0.97 (0.66–1.42) | 8.7 × 10− 1 |
10 | rs10490924 | T | 1.44 (0.99–2.10) | 5.7 × 10−2 | 1.54 (0.99–2.40) | 5.4 × 10− 2 |
6 | rs429608 | A | 1.49 (0.95–2.34) | 7.9 × 10−2 | 1.77 (1.05–2.99) | 3.1 × 10− 2 |
15 | rs920915 | C | 0.75 (0.54–1.05) | 8.9 × 10−2 | 0.82 (0.56–1.21) | 3.2 × 10−1 |
14 | rs8017304 | G | 1.31 (0.93–1.85) | 1.2 × 10−1 | 1.31 (0.88–1.96) | 1.9 × 10−1 |
9 | rs334353 | G | 0.85 (0.59–1.23) | 4.0 × 10−1 | 0.91 (0.59–1.39) | 6.6 × 10− 1 |
8 | rs13278062 | G | 0.88 (0.64–1.23) | 4.6 × 10−1 | 0.85 (0.58–1.25) | 4.1 × 10−1 |
16 | rs1864163 | A | 0.86 (0.57–1.29) | 4.6 × 10−1 | 0.92 (0.58–1.47) | 7.4 × 10− 1 |
6 | rs3812111 | A | 0.89 (0.64–1.24) | 4.9 × 10−1 | 0.81 (0.55–1.19) | 2.8 × 10−1 |
19 | rs2230199 | G | 0.88 (0.58–1.33) | 5.4 × 10−1 | 1.05 (0.65–1.71) | 8.3 × 10− 1 |
22 | rs8135665 | A | 1.09 (0.73–1.63) | 6.6 × 10−1 | 1.35 (0.85–2.17) | 2.1 × 10−1 |
4 | rs4698775 | G | 0.96 (0.67–1.37) | 8.2 × 10−1 | 1.05 (0.69–1.60) | 8.3 × 10− 1 |
19 | rs4420638 | G | 1.05 (0.70–1.57) | 8.3 × 10−1 | 0.90 (0.56–1.46) | 6.8 × 10−1 |
6 | rs3130783 | G | 0.98 (0.66–1.45) | 9.1 × 10−1 | 1.10 (0.69–1.75) | 7.0 × 10− 1 |
1 | rs10737680 | C | 1.01 (0.72–1.42) | 9.6 × 10−1 | 0.78 (0.52–1.17) | 2.2 × 10−1 |