Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

Table 6 Annotation function information for rs12517396, rs16901825, and rs10512851

SNP	LD-r²	LD-D′	ORF	Score of Regulome BD	Function	Binding protein	Regulatory motifs altered
rs12517396	1	1	no	6	Histone modification	no	Bbx, Gfi1, HDAC2, HMG-IY, Hbp1, Nanog, Nkx6, SOX
rs10462070	1	1	no	no date	no	no	AIRE, Ets-disc1, Hnf6, PlZF, pou3f2
rs16901825	0.95	0.86	no	3a	Histone modification	STAT3	ATF3
rs10512851	0.95	0.86	no	5	Chromatin structure	STAT3, CEBPB	Foxp1

Scores of Regulome DB have different meanings. 3a means this SNP is likely to be located in a trans factor binding site and deoxyribonuclease peak area. Five means this SNP is less likely to be located in a trans factor binding site or deoxyribonuclease peak area. Six means others
SNP = single nucleotide polymorphisms, ORF = open reading frame

ISSN: 2326-0254