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Table 6 Annotation function information for rs12517396, rs16901825, and rs10512851

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

SNP LD-r2 LD-D′ ORF Score of Regulome BD Function Binding protein Regulatory motifs altered
rs12517396 1 1 no 6 Histone modification no Bbx, Gfi1, HDAC2, HMG-IY, Hbp1, Nanog, Nkx6, SOX
rs10462070 1 1 no no date no no AIRE, Ets-disc1, Hnf6, PlZF, pou3f2
rs16901825 0.95 0.86 no 3a Histone modification STAT3 ATF3
rs10512851 0.95 0.86 no 5 Chromatin structure STAT3, CEBPB Foxp1
  1. Scores of Regulome DB have different meanings. 3a means this SNP is likely to be located in a trans factor binding site and deoxyribonuclease peak area. Five means this SNP is less likely to be located in a trans factor binding site or deoxyribonuclease peak area. Six means others
  2. SNP = single nucleotide polymorphisms, ORF = open reading frame