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Table 5 Association analysis between rs10462070 and HM/EM in 4 genetic models

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

Group Genotype (n) Genetic Model OR (95% CI) P * Corrected P**
GG GA AA
Control 15 (0.017) 178 (0.198) 706 (0.785)     
HM 5 (0.006) 183 (0.211) 681 (0.784) Homozygote 0.346 (0.123–0.956) 0.032 0.128
     Heterozygote 1.067 (0.845–1.344) 0.590 1
Dominant 1.001 (0.805–1.267) 0.932 1
Recessive 0.341 (0.123–0.942) 0.030 0.128
EM 1 (0.002) 109 (0.225) 375 (0.773) Homozygote 0.126 (0.017–0.954) 0.017 0.068
     Heterozygote 1.153 (0.881–1.509) 0.300 1
Dominant 1.073 (0.823–1.400) 0.603 1
Recessive 0.122 (0.016–0.925) 0.015 0.060
  1. Genotype analyses were conducted for the homozygote model (GG compared with AA), heterozygote model (GA compared with AA), dominant model (GG + GA compared with AA), and the recessive model (GG compared with GA + AA)
  2. HM = high myopia, EM = extreme myopia, OR = odds ratio, CI = confidence interval
  3. * P value has been adjusted for age and sex
  4. ** Corrected P = P × 4 (the number of genetic models)