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Table 4 Association analysis between rs12517396 and HM/EM in 4 genetic models

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

Group Genotype (n) Genetic Model OR (95% CI) P * Corrected P**
AA AC CC
Control 14 (0.016) 178 (0.198) 707 (0.786)     
HM 5 (0.006) 182 (0209) 682 (0.785) Homozygote 0.370 (0.133–1.033) 0.048 0.192
     Heterozygote 1.060 (0.841–1.337) 0.623 1
Dominant 1.010 (0.804–1.267) 0.934 1
Recessive 0.366 (0.131–1.020) 0.045 0.180
EM 1 (0.002) 106 (0.219) 378 (0.779) Homozygote 0.133 (0.018–1.020) 0.023 0.092
     Heterozygote 1.114 (0.849–1.460) 0.435 1
Dominant 1.042 (0.798–1.367) 0.761 1
Recessive 0.131 (0.017–0.996) 0.021 0.084
  1. Genotype analyses were conducted for the homozygote model (AA compared with CC), heterozygote model (AC compared with CC), dominant model (AA+AC compared with CC), and the recessive model (AA compared with AC + CC)
  2. HM = high myopia, EM = extreme myopia, OR = odds ratio, CI = confidence interval
  3. * P value has been adjusted for age and sex
  4. ** Corrected P = P × 4 (the number of genetic models)