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Table 4 Association analysis between rs12517396 and HM/EM in 4 genetic models

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

Group

Genotype (n)

Genetic Model

OR (95% CI)

P *

Corrected P**

AA

AC

CC

Control

14 (0.016)

178 (0.198)

707 (0.786)

    

HM

5 (0.006)

182 (0209)

682 (0.785)

Homozygote

0.370 (0.133–1.033)

0.048

0.192

    

Heterozygote

1.060 (0.841–1.337)

0.623

1

Dominant

1.010 (0.804–1.267)

0.934

1

Recessive

0.366 (0.131–1.020)

0.045

0.180

EM

1 (0.002)

106 (0.219)

378 (0.779)

Homozygote

0.133 (0.018–1.020)

0.023

0.092

    

Heterozygote

1.114 (0.849–1.460)

0.435

1

Dominant

1.042 (0.798–1.367)

0.761

1

Recessive

0.131 (0.017–0.996)

0.021

0.084

  1. Genotype analyses were conducted for the homozygote model (AA compared with CC), heterozygote model (AC compared with CC), dominant model (AA+AC compared with CC), and the recessive model (AA compared with AC + CC)
  2. HM = high myopia, EM = extreme myopia, OR = odds ratio, CI = confidence interval
  3. * P value has been adjusted for age and sex
  4. ** Corrected P = P × 4 (the number of genetic models)