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Table 3 Association analysis between extreme myopia and 4 SNPs in a Han Chinese population

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

SNP

MAF

P-HWE

Allelic P*

OR (95% CI)

Corrected P**

EM

control

EM

Control

rs1384449

0.270

0.288

0.591

0.818

0.309

0.909 (0.765–1.093)

1

rs339501

0.114

0.117

0.051

0.605

0.322

0.987 (0.763–1.277)

1

rs12517396

0.111

0.115

0.021

0.469

0.271

0.979 (0.755–1.270)

1

rs10462070

0.114

0.116

0.017

0.333

0.306

1.016 (0.785–1.315)

1

  1. SNP = single nucleotide polymorphisms, MAF = minor allele frequency, HWE = Hardy-Weinberg equilibrium, OR = odds ratio, CI = confidence interval, EM = extreme myopia
  2. *Allelic P value has been adjusted for age and sex
  3. ** Corrected P = Allelic P × 4 (the number of genotyped SNPs)
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Eye and Vision

ISSN: 2326-0254