Skip to main content

Table 2 Association analysis between high myopia and 4 SNPs in a Han Chinese population

From: Evaluation of FGF10 as a candidate gene for high myopia in a Han Chinese population

SNP

Chr.

Position

Gene

Major/minor allele

MAF

P-HWE

Allelic P*

OR (95% CI)

Corrected P**

Case

Control

Case/Control

rs1384449

5

44376958

FGF10

A/G

0.279

0.288

0.465/0.818

0.242

0.903 (0.761–1.071)

1

rs339501

5

44365531

FGF10

T/C

0.112

0.117

0.099/0.605

0.334

0.990 (0.780–1.257)

1

rs12517396

5

44359424

FGF10

C/A

0.110

0.115

0.053/0.470

0.328

0.989 (0.777–1.258)

1

rs10462070

5

44305647

FGF10

A/G

0.111

0.116

0.051/0.333

0.339

1.009 (0.794–1.283)

1

  1. SNP = single nucleotide polymorphism, Chr. = chromosome, MAF = minor allele frequency, HWE = Hardy-Weinberg equilibrium, OR = odds ratio, CI = confidence interval
  2. *Allelic P value has been adjusted for age and sex
  3. ** Corrected P = Allelic P × 4 (the number of genotyped SNPs)