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Table 3 Top 40 proteins with reduced expression (< 0.5 fold) in C-AME, compared to F-AME

From: A cellular and proteomic approach to assess proteins extracted from cryopreserved human amnion in the cultivation of corneal stromal keratocytes for stromal cell therapy

No.

UniProt Accession No.

Protein

Protein symbol

Mean fold changes**

1

Q8WUF5

RelA-associated inhibitor

PPP1R13L

0.010

2

P58215

Lysyl oxidase homolog 3

LOXL3

0.040

3

P20774

Mimecan

OGN

0.052

4

P07355

Annexin A2

ANXA2

0.057

5

O95171

Sciellin

SCEL

0.069

6

P51991

Heterogeneous nuclear ribonucleoprotein A3

HNRNPA3

0.081

7

P07203

Glutathione peroxidase 1

GPX1

0.092

8

P09429

High mobility group protein B1

HMGB1

0.098

9

O76041

Nebulette

NEBL

0.100

10

P09525

Annexin A4

ANXA4

0.111

11

P63244

Receptor of activated protein C kinase 1

RACK1

0.112

12

P60174

Triosephosphate isomerase

TPI1

0.113

13

Q9UBC9

Small proline-rich protein 3

SPRR3

0.114

14

P23497

Nuclear autoantigen Sp-100

SP100

0.128

15

O15231

Zinc finger protein 185

ZNF185

0.129

16

P0DMV9

Heat shock 70 kDa protein 1B

HSPA1B

0.130

17

Q92541

RTF1 Homolog, Paf1/RNA Polymerase II Complex Component

RTF1

0.131

18

Q8NC51

Plasminogen activator inhibitor 1 RNA-binding protein

SERBP1

0.134

19

P00338

L-lactate dehydrogenase A

LDHA

0.134

20

O43768

Alpha-endosulfine

ENSA

0.135

21

Q9GZT8

NGG1 Interacting Factor 3 Like 1

NIF3L1

0.136

22

P07858

Cathepsin B

CTSB

0.137

23

P20810

Calpastatin

CAST

0.138

24

P00558

Phosphoglycerate kinase 1

PGK1

0.139

25

P56211

cAMP-regulated phosphoprotein 19

ARPP19

0.140

26

Q9P258

Regulator of Chromosome Condensation 2

RCC2

0.147

27

P50238

Cysteine-rich protein 1

CRIP1

0.148

28

P60903

Protein S100-A10

S100A10

0.149

29

P62937

Peptidyl-prolyl cis-trans isomerase A

PPIA

0.150

30

P04075

Fructose-bisphosphate aldolase A

ALDOA

0.151

31

Q01469

Fatty acid-binding protein

FABP5

0.156

32

P31939

Bifunctional purine biosynthesis protein PURH

ATIC

0.158

33

P12277

Creatine kinase B-type

CKB

0.158

34

P00441

Superoxide dismutase [Cu-Zn]

SOD1

0.161

35

Q8WWI1

LIM domain only protein 7

LMO7

0.163

36

P06733

Alpha-enolase

ENO1

0.164

37

O75083

WD repeat-containing protein 1

WDR1

0.166

38

P10915

Hyaluronan and proteoglycan link protein 1

HAPLN1

0.167

39

O43399

Tumour Protein D52 Like 2

TPD52L2

0.168

40

P09211

Glutathione S-transferase P

GSTP1

0.169

  1. F-AME = fresh human amnion extract, C-AME = cryopreserved human amnion extract
  2. *The protein list was ranked by mean fold changes from all 3 amnion samples