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Table 1 Participant characteristics

From: Associated risk factors in the early stage of diabetic retinopathy

 

Control

NDR

MDR

P

n = 86

n = 90

n = 36

 

Eye (OD/OS)

47/39

52/38

21/15

0.892

Age (years)

52.5 ± 9.11

52.7 ± 11.91

56.61 ± 12.25

0.135

Sex (male/female)

31/55

46/44

16/20

0.131

BMI (kg/m2)

23.37 ± 2.84

23.86 ± 2.95

23.9 ± 3.04

0.613

SBP (mmHg)

123.48 ± 13.77

128.4 ± 16.22

132.31 ± 18.23

0.031

DBP (mmHg)

76.88 ± 9.44

79.26 ± 10.44

78.36 ± 9.35

0.373

MAP (mmHg)

118.12 ± 13.34

122.06 ± 14.32

122.46 ± 14.01

0.201

SE (Diopter)

0.15 ± 1.32

−0.18 ± 1.59

0.19 ± 1.48

0.262

BCVA (LogMAR)

0.98 ± 0.14

0.89 ± 0.15

0.86 ± 0.14

< 0.001

AL (mm)

23.24 ± 0.86

23.37 ± 0.94

23.12 ± 0.73

0.320

IOP (mmHg)

13.96 ± 2.65

14.8 ± 2.58

14.88 ± 2.95

0.117

Smoke (Y/N)

–

75/15

25/11

0.082

Alcohol (Y/N)

–

74/16

28/8

0.566

Insulin (Y/N)

–

74/16

24/12

0.058

Duration (years)

–

5.47 ± 5.34

7.02 ± 5.65

0.150

BG (mmol/L)

–

7.85 ± 3.93

8.09 ± 2.38

0.738

HbA1c (%)

–

7.55 ± 1.78

8.17 ± 1.98

0.114

BUN (mmol/L)

–

6.24 ± 5.15

6.04 ± 4.27

0.856

Creatinine (μmol/L)

–

60.62 ± 16.88

73.17 ± 91.96

0.272

TG (mmol/L)

–

1.99 ± 1.73

1.59 ± 1

0.229

TC (mmol/L)

–

4.54 ± 1

4.58 ± 0.96

0.859

HDL-C (mmol/L)

–

1.3 ± 0.37

1.2 ± 0.28

0.194

LDL-C (mmol/L)

–

2.48 ± 0.77

2.45 ± 0.98

0.866

  1. Values are mean ± standard deviation for all subjects in each group. Control = control eyes; NDR = diabetic patients with no diabetic retinopathy; MDR = diabetic patients with mild diabetic retinopathy; BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure; SE = spherical equivalent; BCVA = best corrected visual acuity; AL = axial length; IOP= intraocular pressure; BG = blood glucose; HbA1c= glycosylated hemoglobin; BUN = blood urea nitrogen; TG = triglyceride; TC = total cholesterol; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol. P-values for differences among the three groups were determined by one-way ANOVA (Eye and Sex by Chi-Squared test) and difference between two groups by independent samples t-test. Bold P-value represents < 0.05