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Fig. 1 | Eye and Vision

Fig. 1

From: The use of high resolution anterior segment optical coherence tomography for the characterization of conjunctival lymphoma, conjunctival amyloidosis and benign reactive lymphoid hyperplasia

Fig. 1

Slit lamp and HR-OCT images and histopathology of conjunctival lymphoma. a Slit lamp photograph of a 72-year-old male who presented with a pink, subepithelial nodule on the bulbar conjunctiva in the left eye (black arrow). b HR-OCT through the lesion revealed a normal epithelium but the presence of a large, hyporeflective, homogenous appearing subepithelial lesion infiltrated with monomorphic dot-like infiltrates (white arrows). A hyperreflective band of tissue is noted above and below the infiltrate. c HR-OCT images corresponded with histopathology, in which a moderately dense, monomorphic lymphocytic cell population was present within the substantia propria (hematoxylin and eosin; original magnification × 100). d Immunohistochemical studies were positive for CD20 (shown in image; original magnification × 100) and negative for C5 and CD10. The plasma cells were monoclonal for kappa light chain by in situ hybridization (ISH), consistent with mucosa-associated lymphoid tissue (MALT) lymphoma. e After 17 sessions of external beam radiation therapy, the subepithelial lesion resolved clinically. f On HR-OCT, there was complete normalization of the conjunctival architecture with resolution of the subepithelial lesion

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Eye and Vision

ISSN: 2326-0254