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Table 1 Summary of significant functional slit-lamp biomicroscopy findings on the ocular surface

From: A review of functional slit lamp biomicroscopy

Reference

N (eyes)

Group

Blood flow velocity (mm/s)

Blood flow rate (pl/s)

Vessel diameter (μm)

Dbox

D0

Xu et al. [18]

20

9 am vs. 5 pm

0.62 ± 0.31 (9 am)

0.63 ± 0.25 (5 pm)

166.20 ± 85.78 (9 am)

158.03 ± 69.57 (5 pm)

21.68 ± 2.47 (9 am)

21.05 ± 2.79 (5 pm)

1.61 ± 0.06 (9 am)

1.64 ± 0.04 (5 pm)

(*)

1.68 ± 0.04 (9 am)

1.70 ± 0.04 (5 pm)

(*)

Jiang et al. [21]

6

Baseline vs. 6h after CL wear

0.60 ± 0.12 (B)

0.88 ± 0.21 (6 h)

(*)

129.8 ± 59.9 (B)

207.2 ± 81.3 (6h)

(*)

18.8 ± 2.7 (B)

19.6 ± 2.4 (6 h)

(*)

1.63 ± 0.05 (B)

1.69 ± 0.03 (6 h)

(*)

1.71 ± 0.03 (B)

1.76 ± 0.03 (6 h)

(*)

Chen et al. [32]

22

Baseline vs. 6h after CL wear

0.51 ± 0.20 (B)

0.65 ± 0.22 (6 h)

(*)

 

17.8 ± 1.8 (B)

17.9 ± 1.2 (6 h)

  

Shi et al. [23]

60

HCL vs. NCL

0.59 ± 0.19 (H)

0.48 ± 0.17 (N)

(*)

119 ± 38 (H)

92 ± 39 (N)

(*)

16.9 ± 1.3 (H)

17.3 ± 1.6 (N)

1.64 ± 0.05 (H)

1.61 ± 0.05 (N)

(*)

1.71 ± 0.05 (H)

1.69 ± 0.04 (N)

(*)

Hu et al. [33]

166

HCL vs. NCL

Female vs. Male

0.61 ± 0.15 (H)

0.50 ± 0.14 (N)

(*)

0.51 ± 0.14 (F)

0.42 ± 0.13 (M)

(*)

140 (H)

94.5 (N)

(*)

93.7 (F)

80.4 (M)

(*)

18.3 (H)

16.4 (N)

(*)

16.2 (F)

16.6 (M)

1.67 (H)

1.62 (N)

(*)

1.61 (F)

1.62(M)

1.75 (H)

1.69 (N)

(*)

1.68 (F)

1.69 (M)

Deng et al. [22]

16

Tarsal conjunctiva (T)

vs. Lid wiper (L)

vs.Bulbar conjunctiva (B)

   

1.731 ± 0.026

1.740 ± 0.030 (T*)

1.411 ± 0.116

1.548 ± 0.079 (L*)

1.587 ± 0.059

1.632 ± 0.060 (B*)

 

Chen et al. [24]

56

Baseline vs. After an air puff

0.50 ± 0.15 (B) 0.55 ± 0.17 (A)

(*)

 

22.13 ± 1.84 (B)

22.21 ± 2.04 (A)

1.64 ± 0.04 (B)

1.65 ± 0.04 (A)

 

Chen et al. [25]

50

DED patients vs. Healthy human

0.59 ± 0.09 (D)

0.47 ± 0.12 (H)

(*)

169.5 ± 1.8 (D)

107.2 ± 49.6 (H)

(*)

21.8 ± 1.8 (D)

17.9 ± 2.2 (H)

(*)

1.65 ± 0.04 (D)

1.60 ± 0.07 (H)

(*)

 
  1. CL = contact lens; HCL = Habitual contact lens; NCL = Noncontact lens; DED = Dry eye disease
  2. (*), P <0.05
  3. Bold fonts indicate statistical differences in data comparison