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Table 1 Summary of significant functional slit-lamp biomicroscopy findings on the ocular surface

From: A review of functional slit lamp biomicroscopy

Reference N (eyes) Group Blood flow velocity (mm/s) Blood flow rate (pl/s) Vessel diameter (μm) Dbox D0
Xu et al. [18] 20 9 am vs. 5 pm 0.62 ± 0.31 (9 am)
0.63 ± 0.25 (5 pm)
166.20 ± 85.78 (9 am)
158.03 ± 69.57 (5 pm)
21.68 ± 2.47 (9 am)
21.05 ± 2.79 (5 pm)
1.61 ± 0.06 (9 am)
1.64 ± 0.04 (5 pm)
(*)
1.68 ± 0.04 (9 am)
1.70 ± 0.04 (5 pm)
(*)
Jiang et al. [21] 6 Baseline vs. 6h after CL wear 0.60 ± 0.12 (B)
0.88 ± 0.21 (6 h)
(*)
129.8 ± 59.9 (B)
207.2 ± 81.3 (6h)
(*)
18.8 ± 2.7 (B)
19.6 ± 2.4 (6 h)
(*)
1.63 ± 0.05 (B)
1.69 ± 0.03 (6 h)
(*)
1.71 ± 0.03 (B)
1.76 ± 0.03 (6 h)
(*)
Chen et al. [32] 22 Baseline vs. 6h after CL wear 0.51 ± 0.20 (B)
0.65 ± 0.22 (6 h)
(*)
  17.8 ± 1.8 (B)
17.9 ± 1.2 (6 h)
  
Shi et al. [23] 60 HCL vs. NCL 0.59 ± 0.19 (H)
0.48 ± 0.17 (N)
(*)
119 ± 38 (H)
92 ± 39 (N)
(*)
16.9 ± 1.3 (H)
17.3 ± 1.6 (N)
1.64 ± 0.05 (H)
1.61 ± 0.05 (N)
(*)
1.71 ± 0.05 (H)
1.69 ± 0.04 (N)
(*)
Hu et al. [33] 166 HCL vs. NCL
Female vs. Male
0.61 ± 0.15 (H)
0.50 ± 0.14 (N)
(*)
0.51 ± 0.14 (F)
0.42 ± 0.13 (M)
(*)
140 (H)
94.5 (N)
(*)
93.7 (F)
80.4 (M)
(*)
18.3 (H)
16.4 (N)
(*)
16.2 (F)
16.6 (M)
1.67 (H)
1.62 (N)
(*)
1.61 (F)
1.62(M)
1.75 (H)
1.69 (N)
(*)
1.68 (F)
1.69 (M)
Deng et al. [22] 16 Tarsal conjunctiva (T)
vs. Lid wiper (L)
vs.Bulbar conjunctiva (B)
    1.731 ± 0.026
1.740 ± 0.030 (T*)
1.411 ± 0.116
1.548 ± 0.079 (L*)
1.587 ± 0.059
1.632 ± 0.060 (B*)
 
Chen et al. [24] 56 Baseline vs. After an air puff 0.50 ± 0.15 (B) 0.55 ± 0.17 (A)
(*)
  22.13 ± 1.84 (B)
22.21 ± 2.04 (A)
1.64 ± 0.04 (B)
1.65 ± 0.04 (A)
 
Chen et al. [25] 50 DED patients vs. Healthy human 0.59 ± 0.09 (D)
0.47 ± 0.12 (H)
(*)
169.5 ± 1.8 (D)
107.2 ± 49.6 (H)
(*)
21.8 ± 1.8 (D)
17.9 ± 2.2 (H)
(*)
1.65 ± 0.04 (D)
1.60 ± 0.07 (H)
(*)
 
  1. CL = contact lens; HCL = Habitual contact lens; NCL = Noncontact lens; DED = Dry eye disease
  2. (*), P <0.05
  3. Bold fonts indicate statistical differences in data comparison