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Table 1 Stem cells assayed for corneal stroma regeneration: evidence of keratocyte or keratocyte-like differentiation and their potential autologous application

From: Cellular therapy of the corneal stroma: a new type of corneal surgery for keratoconus and corneal dystrophies

 

CSSC

BM-MSC

ADASC

UMSC

ESC

iPSC

Keratocyte differentiation in vitro demonstrated

Yes

Yes

Yes

Yes

Yes

Yes

Keratocyte differentiation in vivo demonstrated

Yes

Yes

Yes

Yes

No

No

Possible autologous use

Yes/No

Yes

Yes

Yes/No

No

Yes

  1. CSSCs = corneal stroma stem cells; MSC = mesenchymal stem cell; BM = bone marrow; ADASC = adipose-derived adult stem cell; UMSC = umbilical MSC; ESC = embryonic stem cell; iPSC = induced pluripotent stem cell