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Table 1 Stem cells assayed for corneal stroma regeneration: evidence of keratocyte or keratocyte-like differentiation and their potential autologous application

From: Cellular therapy of the corneal stroma: a new type of corneal surgery for keratoconus and corneal dystrophies

  CSSC BM-MSC ADASC UMSC ESC iPSC
Keratocyte differentiation in vitro demonstrated Yes Yes Yes Yes Yes Yes
Keratocyte differentiation in vivo demonstrated Yes Yes Yes Yes No No
Possible autologous use Yes/No Yes Yes Yes/No No Yes
  1. CSSCs = corneal stroma stem cells; MSC = mesenchymal stem cell; BM = bone marrow; ADASC = adipose-derived adult stem cell; UMSC = umbilical MSC; ESC = embryonic stem cell; iPSC = induced pluripotent stem cell