Fig. 2

Autologous h-ADASC corneal stroma implantation for advanced keratoconus. a) Slit lamp picture one year after the procedure; b) Topographic changes (Pentacam) between preop and 12 months after surgery. Observe the stability of the keratometric parameters; c) Corneal confocal biomicroscopy pictures at the surgical plane in the first postoperative month. Stem cell survival is confirmed by the presence of cells showing a more rounded morphology (white arrows) (image corresponds to an area of 100 × 100 μm); d) AS-OCT picture 1 year postoperatively. Note the patched hyper-reflective areas (red arrows) at the level of the stromal pocket compatible with areas of new collagen production