Manual mid-stromal dissection as a low risk procedure to stabilize mild to moderate progressive keratoconus

Table 3 Pre- and postoperative pachymetry values

Case no.	Max FU years (m)	Central corneal thickness (μm)				Δ Pre-op to latest FU (%)	Thinnest point thickness (μm)				Δ Pre-op to latest FU (%)	Remarks
Case no.	Max FU years (m)	Pre-op	1 yr. FU	2 yr. FU	Latest FU	Δ Pre-op to latest FU (%)	Pre-op	1 yr. FU	2 yr. FU	Latest FU	Δ Pre-op to latest FU (%)	Remarks
1	9.4 (113)	505	502	509	490	−3.0	492	487	496	478	−2.8
2^a	3.1 (37)	513	510	508	509	−0.8	483	487	472	492	+ 1.9
3^a	3.0 (36)	534	520	530	524	−1.9	504	487	482	493	−2.2
4	9.2 (110)	466	469	n.a.	473	+ 1.5	451	449	n.a.	444	−1.6
5	3.9 (47)	414	410	406	404	−2.4	336	321	328	329	− 2.1	Bowman Layer Transplantation (47 m)
6^b	8.7 (104)	470	475	473	458	−2.6	446	458	453	441	−1.1
7	8.8 (106)	n.a.	(414)	(419)	(423)		n.a.	(407)	(408)	(429)
8	7.3 (87)	568	571	564	557	−1.9	511	497	502	506	−1.0
9	6.8 (82)	470	456	488	476	+ 1.3	419	344	395	379	−9.5
10	8.5 (102)	339	350	325	329	−2.9	313	292	287	274	−12.5
11	7.3 (87)	497	486	479	486	−2.2	481	465	456	451	−6.2
12	8.1 (97)	471	481	n.a.	477	+ 1.3	466	480	n.a.	471	+ 1.1
13^b	7.7 (92)	469	467	469	457	−2.6	434	438	442	440	+ 1.4
14	1.6 (19)	459	385	n.a.	385	−16.1	366	305	n.a.	305	−16.7	Bowman Layer Transplantation (19 m)
15	6.9 (83)	392	376	377	369	−5.9	338	332	325	322	−4.7
16	5.8 (70)	475	453	458	453	−4.6	465	440	453	445	−4.3
Average	6.6 (79.5)	469	461	466	456		434	419	424	418
SD	2.4 (29.4)	56	59	67	61		65	76	73	76
P-value (pre-op to FU)			0.121	0.126				0.035	0.010

FU = follow-up; Pre-op = preoperative; m = months; yr. = year; μm = micrometer; n.a. = not available; SD = standard deviation
^a,bNote that two patients (cases no. 2, 3, 6, and 13) underwent bilateral manual crosslinking
Case no. 7 was excluded from pachymetry analysis due to a preoperative measurement of insufficient quality

ISSN: 2326-0254