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Table 2 Pre- and postoperative corneal curvature

From: Manual mid-stromal dissection as a low risk procedure to stabilize mild to moderate progressive keratoconus

Case no.

Max FU years (m)

SimK-value (D)

Δ Pre-op to latest FU (D)

Kmax (D)

Δ Pre-op to latest FU (D)

Remarks

Pre-op

1 yr. FU

2 yr. FU

Latest FU

Pre-op

1 yr. FU

2 yr. FU

Latest FU

1

9.4 (113)

46.2

46.6

46.4

47.2

1.0

51.4

47.1

51.1

52.8

1.4c

 

2a

3.1 (37)

44.8

44.5

45.1

44.5

−0.3

59.9

60.5

60.1

59.8

−0.1

 

3a

3.0 (36)

43.5

44.5

43.2

43.3

−0.2

58.6

59.4

58.1

58.4

− 0.2

 

4

9.2 (110)

45.8

45.6

n.a.

45.8

0

49.9

48.2

n.a.

50.3

0.4

 

5

3.9 (47)

53.4

54.0

55.3

56.2

2.8

71.8

71.1

73.5

74.5

2.7c

Bowman Layer Transplantation (47 m)

6b

8.7 (104)

49.0

49.0

49.1

48.9

−0.1

56.5

57.1

57.8

58.5

2.0c

 

7

8.8 (106)

n.a.

(52.2)

(52.2)

(52.4)

 

n.a.

(58.4)

(57.8)

(58.7)

  

8

7.3 (87)

50.1

49.5

50.2

51.3

1.2

58.6

57.2

57.1

57.6

−1.0

 

9

6.8 (82)

37.1

38.0

38.0

38.6

1.5

46.4

46.5

46

52.0

5.6c

 

10

8.5 (102)

52.0

50.9

52.8

57.5

5.5

58.7

60.1

62.9

70.7

12.0c

 

11

7.3 (87)

42.5

42.4

42.6

42.3

−0.2

53.4

52.8

53.7

52.8

−0.6

 

12

8.1 (97)

47.6

46.9

n.a.

47.2

−0.4

49.4

48.3

n.a.

47.9

−1.1

 

13b

7.7 (92)

48.3

48.1

47.8

49.2

0.9

55.5

55.9

54.6

59.9

4.4c

 

14

1.6 (19)

61.9

60.1

n.a.

n.a.

−1.8

72.5

76.8

n.a.

n.a.

4.3c

Bowman Layer Transplantation (19 m)

15

6.9 (83)

58.2

57.9

60.0

61.5

3.3

69.2

70.9

78.1

74.3

5.1c

 

16

5.8 (70)

51.1

50.8

51.2

52.2

1.1

60.3

59.9

60.1

62.3

2.0c

 

Average

6.6 (79.5)

48.8

48.6

48.5

49.7

+ 1.0

58.1

58.1

59.4

60.6

2.5

 

SD

2.4 (29.4)

6.2

5.7

6.0

6.7

1.8

7.9

9.2

8.9

9.4

3.5

 

P-value (pre-op to FU)

0.357

0.060

   

0.970

0.223

   
  1. FU = follow-up; Max = maximum; D = diopter; Pre-op = preoperative; yr. = year; m = months; Δ = difference; simK = simulated keratometry; Kmax = maximum keratometry value; SD = standard deviation; n.a. = not available
  2. a,bNote that two patients (cases no. 2, 3, 6, and 13) underwent bilateral manual crosslinking
  3. cProgression of corneal ectasia after mid-stromal manual dissection
  4. Case no. 7 was excluded from keratometry analysis due to a preoperative measurement of insufficient quality