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Table 1 Demographic and ocular characteristics

From: Evaluation of markers of outcome in real-world treatment of diabetic macular edema

Demographic characteristics (N = 122 patients; 68 RE and 54 LE)

Age (years)

 Mean ± SD

65.2 ± 8.9

 Median (range)

66 (46–85)

Sex

 Male

66 (54.1%)

 Female

56 (45.9%)

Duration of diabetes (years)

 1–15

55 (45.1%)

 16–25

52 (42.6%)

  > 25

15 (12.3%)

HbA1c (%)

  ≤ 7

31 (25.4%)

  > 7 and < 8

44 (36.1%)

  ≥ 8

47 (38.5%)

Hypertensiona

 Yes

75 (61.5%)

 No

47 (38.5%)

Insulin

 Yes

64 (52.5%)

 No

58 (47.5%)

Ocular characteristics (N = 122 eyes)

Lens status

 Phakic

80 (65.6%)

 Pseudophakic

42 (34.4%)

Intravitreal injection received

 RNZ only

93 (76.2%)

 AFL only

14 (11.5%)

 Both

15 (12.3%)

Laser

 Yes

68 (55.7%)

 No

54 (44.3%)

Baseline BCVA (L)

 Mean ± SD

63.2 ± 12.7

 Median (range)

67.0 (24.0–78.0)

Baseline CRT (μm)

 Mean ± SD

432.4 ± 107.0

 Median (range)

400.5 (289.0–776.0)

Baseline SFCT (μm)

 Mean ± SD

346.6 ± 75.6

 Median (range)

345.0 (124.0–580.0)

Baseline EZ

 Intact

80 (65.6%)

 Disrupted

41 (33.6%)

 Unreadable

1 (0.8%)

3 M EZ

 Intact

89 (73.0%)

 Disrupted

33 (27.0%)

Baseline SND

 Yes

27 (22.1%)

 No

95 (77.9%)

  1. Abbreviations: RE=right eye; LE=left eye; HbA1c=level of glycated hemoglobin (percentage); RNZ=ranibizumab; AFL=aflibercept; BCVA=best corrected visual acuity scored using the ETDRS letters (L) chart; CRT=central retinal thickness; SFCT=subfoveal choroidal thickness; EZ=ellipsoid zone; 3 M EZ=re-rating of the EZ after the loading dose; SND=subfoveal neuroretinal detachment; SBP=systolic blood pressure; DBP=diastolic blood pressure; MAP=mean arterial blood pressure
  2. aSBP and DBP were measured at baseline and whenever coming back to the hospital including visits and injections. MAP was determined using the formula: MAP = DBP + 1/3 × (SBP – DBP). The patient was rated as hypertensive whenever 2 MAP values above 110 mmHg were recorded in two separate visits to the hospital