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Table 2 Comparison of BSCVA and Kmax between HPMC vs. Dextran-treated Groups

From: Corneal collagen crosslinking in patients treated with dextran versus isotonic hydroxypropyl methylcellulose (HPMC) riboflavin solution: a retrospective analysis

  HPMC Group Dextran Group  
Mean n-value Mean n-value p-value
Change in BSCVA (SD)
1 Month 0.16 (0.15) 17 −0.05 (0.20) 30 < 0.001
6 Months 0.00 (0.17) 15 − 0.13 (0.17) 27 < 0.05
 12 Months −0.03 (0.16) 15 −0.16 (0.22) 20 0.07
24 Months −0.01 (0.13) 9 −0.18 (0.17) 15 < 0.05
Change in Kmax (SD)
1 Month 3.32 (4.89) 11 0.12 (2.23) 25 < 0.05
 6 Months −0.20 (2.22) 12 −1.29 (3.12) 24 0.29
 12 Months −0.45 (2.35) 11 −2.41 (6.21) 16 0.33
 24 Months −1.82 (3.38) 9 −1.45 (2.65) 11 0.78
  1. bolded values represent statistical significance
  2. BSCVA= best spectacle corrected visual acuity, HPMC= hydroxypropyl methylcellulose, SD= standard deviation