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Fig. 2 | Eye and Vision

Fig. 2

From: Altered birefringence of peripapillary retinal nerve fiber layer in multiple sclerosis measured by polarization sensitive optical coherence tomography

Fig. 2

Polarization sensitive optical coherence tomography (PS-OCT) for imaging the pRNFL of a RRMS patient and healthy subject. Images of the pRNFL structure (a and b) and retardation (c and d) were obtained. The outlined pRNFL boundaries acquired from the OCT intensity images (a and b) were projected into the retardation images (c-f), creating segmented pRNFL with retardation (e and f). Averaged retardations of 512 A-scans from each quadrant were analyzed and plotted as a function of the scan depth in the RNFL. Scatter plots (g and h) were the averaged retardation in the inferior quadrant as a function of the scan depth. The slopes of the linear regression were defined as the PR/UD of the pRNFL. The PR/UD of the inferior pRNFL in the MS patient was 7.7 degrees/100 μm, which was lower than that in the control (12.0 degrees/100 μm). T = temporal; S = superior; N = nasal; and I = inferior. Bars = 500 μm

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