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Table 1 Effects of SCH 23390, picrotoxin and combined picrotoxin + SCH 23390 application on the latency of the ERG b- and d-waves, obtained at different time periods (minutes from the beginning of the experiment)

From: Effects of dopamine D1 receptor blockade on the ERG b- and d-waves during blockade of ionotropic GABA receptors

Group Latency (ms) 10 min 21 min 37 min 48 min
R b-wave 115 ± 4.92 112 ± 6.58 111 ± 3.09 110 ± 5.20
d-wave 104 ± 5.05 100 ± 7.14 105 ± 8.54 97 ± 8.45
SCH b-wave 113 ± 3.47 117 ± 5.28   
d-wave 95 ± 6.66 106 ± 8.77   
PT b-wave 124 ± 7.36   135 ± 6.74 133 ± 7.21
    p < 0.008  
d-wave 104 ± 6.91   127 ± 7.60 127 ± 7.29
    p < 0.00002  
PT+SCH b-wave 127 ± 5.21   133 ± 5.98 133 ± 7.05
    p < 0.042  
d-wave 112 ± 6.81   131 ± 7.60 127 ± 9.5
    p < 0.018  
  1. The statistical significance of the differences between the values obtained before (10 min) and after drug application (37 min) is evaluated using paired t-test. Means ± SEM are shown
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Eye and Vision

ISSN: 2326-0254