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Table 1 Previously suggested parameters used to determine progression of ectatic disease

From: Assessing progression of keratoconus: novel tomographic determinants

Suggested Parameter

Value Representing Progression

Validated

Spherical power, and higher order irregular astigmatism [32, 35]

Positive Rate of Change per Year

No

Spherical component, regular astigmatism, decentration component, and higher order irregularity [37]

Positive Rate of Change per Year

No

Kmax (steepest K) [27, 38]

≥ 1.00 D increase

No

Kmax – Kmin [38]

≥ 1.00 D increase

No

Kmean (average of Kmax and Kmin)

≥ 0.75 D increase

No

Pachymetry [38]

≥ 2 % decrease in central thickness

No

Back optic zone radius of the best fitting contact lens [27]

0.1 mm or more decrease

No

Increase in the central K power [25]

≥ 1.50 D increase from baseline

No

Manifest cylinder [38]

Increase of ≥ 1.00 D in 24 months

No

Manifest refraction spherical equivalent change (MRSE) [27, 38]

≥ 0.50 D

No

ISV [22]

Specific values for each KCN stage

No

IHA [22]

Specific values for each KCN stage

No

  1. ISV = index of surface variance, IHA = index of height asymmetry, KCN = keratoconus