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Table 5 Comparison of the magnitude of residuals of the linear mixed effect model before and after registration

From: Effect of image registration on longitudinal analysis of retinal nerve fiber layer thickness of non-human primates using Optical Coherence Tomography (OCT)

RNFL feature Linear mixed effects model for residual
Intercept (μm) Slope Of reg i,t p value for slope
All rings 2.5198 0.3877 0.4075
Temporal 5.3737 −1.8789 0.0425*
Inferior 4.5483 0.0420 0.9595
Nasal 5.1851 −1.8431 0.0259*
Superior 5.6397 −1.4297 0.0773
Clock hour 01 5.3477 −1.3711 0.0944
Clock hour 02 6.0659 −1.9699 0.0359*
Clock hour 03 4.7984 −1.3750 0.0797
Clock hour 04 9.3879 −6.3046 <0.0001*
Clock hour 05 8.7581 −3.5554 0.0018*
Clock hour 06 6.5226 0.6532 0.5933
Clock hour 07 8.0791 −2.8944 0.0325*
Clock hour 08 6.5612 −2.2646 0.0488*
Clock hour 09 7.6976 −4.3798 0.0024*
Clock hour 10 8.7744 −4.9544 0.0003*
Clock hour 11 7.6400 −2.6737 0.0229*
Clock hour 12 7.1031 −2.6395 0.0060*
  1. Coefficients and the p values of the coefficients for comparing residuals of linear mixed effects models of RNFL features vs. days before registration (reg i,t  = 0) and after registration by LPCC_MSBV algorithm (reg i,t  = 1). Most of the slopes are significantly negative (p < 0.05), which mean that the magnitude of the residuals decreased after registration.
  2. *Slopes were negative and p values were smaller than 0.05.