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Table 1 Visual and refractive outcomes after SMILE

From: Small incision lenticule extraction (SMILE) history, fundamentals of a new refractive surgery technique and clinical outcomes

Study Eyes Follow-up Preop SEQ (D) Postop SEQ (D) ±0.50 D 20/20 CDVA preop UDVA 20/20 or better postop UDVA 20/25 or better postop Loss 2 lines CDVA
Sekundo 2011 [11] 91 6 months −4.75 ± 1.56 −0.01 ± 0.49 80% --- 84% 92% 1.1%
Shah 2011 [12] 51 6 months −4.87 ± 2.16 +0.03 ± 0.30 91% 67% 62% 79% 0.0%
−1.75 to −10.00 −0.75 to +0.75
Vestergaard 2012 [17] 127 3 months −7.18 ± 1.57 −0.09 ± 0.45 77% --- 37% 73% 0.4%
−1.63 to −11.50 −1.63 to +1.38
Hjortdal 2012 [13] 670 3 months −7.19 ± 1.30 −0.25 ± 0.44 80% 88% 61% 84% 2.4%
−1.63 to −9.88 −2.13 to +1.38
Wang 2013 [18] 88 3 months --- −0.11 ± 0.29 --- --- 100% --- 0.0%
Kamiya 2014 [19] 26 6 months −4.21 ± 1.63 +0.01 100% 100% 96% --- 0.0%
−1.25 to −8.25  
Sekundo 2014 [20] 54 1 year −4.68 ± 1.29 −0.19 ± 0.19 92% 98% 88% 98% 0.0%
−2.00 to −9.00 −1.00 to +0.50
Agca 2014 [21] 40 1 year −4.03 ± 1.61 −0.33 ± 0.25 95% --- 65% 95% 0.0%
Lin 2014 [22] 60 3 months −5.13 ± 1.75 −0.09 ± 0.38 --- --- 85% 93% 1.7%
−1.75 to −7.75 −1.25 to +0.75
  1. SMILE: small incision lenticule extraction; Preop: preoperative; Postop: postoperative; SEQ: spherical equivalent refraction; CDVA: corrected distance visual acuity; UDVA: uncorrected distance visual acuity.