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Table 5 Intraoperator repeatability for epithelium thickness obtained using MS-39 in total patients

From: Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium

Parameter

Observer

Mean ± SD (μm)

Sw (μm)

TRT (μm)

CoV (%)

ICC (95% CI)

CET

1st

50.40 ± 5.54

1.34

3.70

2.65

0.944 (0.926 to 0.958)

 

2nd

50.97 ± 5.86

1.41

3.90

2.77

0.944 (0.927 to 0.958)

TET

1st

42.88 ± 4.21

1.89

5.23

4.41

0.822 (0.773 to 0.864)

 

2nd

43.24 ± 4.70

1.99

5.50

4.60

0.840 (0.796 to 0.878)

S1

1st

53.97 ± 6.10

1.40

3.89

2.60

0.949 (0.933 to 0.962)

 

2nd

54.06 ± 5.94

1.59

4.40

2.94

0.932 (0.911 to 0.948)

S3

1st

51.16 ± 4.63

2.06

5.72

4.04

0.825 (0.773 to 0.868)

 

2nd

51.09 ± 4.65

2.34

6.47

4.57

0.784 (0.727 to 0.834)

I1

1st

49.18 ± 5.21

1.53

4.24

3.11

0.919 (0.894 to 0.939)

 

2nd

49.63 ± 5.34

1.43

3.97

2.89

0.931 (0.911 to 0.948)

I3

1st

51.50 ± 5.27

1.61

4.46

3.13

0.912 (0.885 to 0.934)

 

2nd

51.78 ± 5.13

1.71

4.72

3.29

0.897 (0.867 to 0.922)

N1

1st

52.17 ± 6.25

1.40

3.89

2.69

0.951 (0.936 to 0.963)

 

2nd

54.13 ± 5.49

1.46

4.04

2.69

0.933 (0.912 to 0.949)

N3

1st

54.93 ± 5.45

1.69

4.68

3.08

0.910 (0.883 to 0.932)

 

2nd

55.74 ± 5.09

1.60

4.42

2.86

0.908 (0.880 to 0.930)

T1

1st

51.41 ± 5.06

1.55

4.30

3.02

0.911 (0.885 to 0.933)

 

2nd

50.42 ± 6.05

1.67

4.63

3.32

0.927 (0.905 to 0.945)

T3

1st

53.94 ± 4.79

1.60

4.42

2.96

0.897 (0.866 to 0.922)

 

2nd

53.44 ± 4.78

1.56

4.32

2.92

0.901 (0.871 to 0.925)

  1. SD = standard deviation; Sw = within-subject standard deviation; TRT = test-retest repeatability (2.77 Sw); CoV = coefficient of variation; ICC = intraclass correlation coefficient; CET = central epithelium thickness; TET = thinnest epithelium thickness; S1 (S3) = corneal apex superior at 1 mm (3 mm); I1 (I3) = corneal apex inferior at 1 mm (3 mm); N1 (N3) = corneal apex nasal at 1 mm (3 mm); T1 (T3) = corneal apex temporal at 1 mm (3 mm)