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Table 4 Intraoperator repeatability for epithelium thickness obtained using MS-39 in severe keratoconus patients

From: Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium

Parameter

Observer

Mean ± SD (μm)

Sw (μm)

TRT (μm)

CoV (%)

ICC (95% CI)

CET

1st

47.27 ± 5.69

1.90

5.26

4.02

0.896 (0.836 to 0.938)

 

2nd

48.09 ± 6.40

1.75

4.84

3.64

0.929 (0.887 to 0.957)

TET

1st

39.96 ± 3.81

2.04

5.65

5.10

0.760 (0.639 to 0.852)

 

2nd

40.50 ± 5.59

2.33

6.46

5.76

0.844 (0.759 to 0.905)

S1

1st

52.58 ± 8.55

1.87

5.19

3.57

0.953 (0.925 to 0.973)

 

2nd

52.74 ± 7.92

2.03

5.61

3.84

0.937 (0.900 to 0.963)

S3

1st

53.24 ± 4.84

2.33

6.46

4.38

0.799 (0.692 to 0.878)

 

2nd

52.91 ± 4.58

2.74

7.58

5.17

0.711 (0.579 to 0.817)

I1

1st

46.74 ± 5.47

2.24

6.21

4.79

0.849 (0.766 to 0.909)

 

2nd

47.04 ± 5.42

1.83

5.06

3.88

0.894 (0.835 to 0.936)

I3

1st

49.90 ± 6.49

1.53

4.24

3.07

0.946 (0.913 to 0.968)

 

2nd

50.28 ± 6.36

1.85

5.12

3.68

0.920 (0.874 to 0.952)

N1

1st

49.76 ± 7.17

1.89

5.25

3.81

0.933 (0.893 to 0.961)

 

2nd

52.25 ± 6.54

1.98

5.48

3.79

0.914 (0.864 to 0.948)

N3

1st

57.05 ± 6.67

2.00

5.53

3.50

0.916 (0.866 to 0.950)

 

2nd

57.95 ± 6.06

1.67

4.61

2.87

0.928 (0.886 to 0.957)

T1

1st

49.74 ± 5.93

2.14

5.93

4.30

0.880 (0.812 to 0.928)

 

2nd

48.69 ± 7.62

2.12

5.88

4.36

0.926 (0.883 to 0.956)

T3

1st

55.46 ± 6.38

1.78

4.92

3.20

0.926 (0.882 to 0.956)

 

2nd

54.83 ± 5.75

1.87

5.17

3.41

0.902 (0.845 to 0.941)

  1. SD = standard deviation; Sw = within-subject standard deviation; TRT = test-retest repeatability (2.77 Sw); CoV = coefficient of variation; ICC = intraclass correlation coefficient; CET = central epithelium thickness; TET = thinnest epithelium thickness; S1 (S3) = corneal apex superior at 1 mm (3 mm); I1 (I3) = corneal apex inferior at 1 mm (3 mm); N1 (N3) = corneal apex nasal at 1 mm (3 mm); T1 (T3) = corneal apex temporal at 1 mm (3 mm)