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Table 3 Intraoperator repeatability for epithelium thickness obtained using MS-39 in moderate keratoconus patients

From: Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium

Parameter

Observer

Mean ± SD (μm)

Sw (μm)

TRT (μm)

CoV (%)

ICC (95% CI)

CET

1st

50.35 ± 5.73

1.31

3.64

2.61

0.949 (0.914 to 0.972)

 

2nd

51.25 ± 6.12

1.59

4.41

3.10

0.935 (0.892 to 0.964)

TET

1st

43.20 ± 3.89

1.85

5.12

4.28

0.804 (0.689 to 0.886)

 

2nd

43.30 ± 3.51

1.89

5.23

4.36

0.758 (0.627 to 0.857)

S1

1st

55.23 ± 5.75

1.29

3.59

2.34

0.951 (0.917 to 0.973)

 

2nd

55.47 ± 6.05

1.66

4.59

2.99

0.929 (0.881 to 0.960)

S3

1st

51.33 ± 4.42

1.87

5.19

3.65

0.840 (0.736 to 0.911)

 

2nd

51.85 ± 5.00

2.37

6.57

4.58

0.804 (0.689 to 0.887)

I1

1st

47.95 ± 4.64

1.23

3.41

2.57

0.933 (0.887 to 0.963)

 

2nd

48.89 ± 4.74

1.52

4.21

3.11

0.904 (0.841 to 0.946)

I3

1st

52.79 ± 5.11

1.62

4.50

3.08

0.905 (0.843 to 0.947)

 

2nd

53.26 ± 4.93

1.47

4.06

2.76

0.916 (0.861 to 0.953)

N1

1st

52.56 ± 6.53

1.31

3.62

2.48

0.961 (0.934 to 0.979)

 

2nd

55.19 ± 5.53

1.21

3.36

2.20

0.953 (0.921 to 0.974)

N3

1st

55.27 ± 5.16

1.60

4.42

2.89

0.910 (0.850 to 0.950)

 

2nd

56.41 ± 4.58

1.63

4.51

2.88

0.884 (0.809 to 0.934)

T1

1st

51.09 ± 5.33

1.50

4.16

2.94

0.925 (0.874 to 0.958)

 

2nd

49.88 ± 5.63

1.77

4.91

3.55

0.907 (0.846 to 0.948)

T3

1st

54.27 ± 4.01

1.59

4.40

2.93

0.858 (0.769 to 0.919)

 

2nd

53.90 ± 4.65

1.38

3.83

2.56

0.917 (0.861 to 0.954)

  1. SD = standard deviation; Sw = within-subject standard deviation; TRT = test-retest repeatability (2.77 Sw); CoV = coefficient of variation; ICC = intraclass correlation coefficient; CET = central epithelium thickness; TET = thinnest epithelium thickness; S1 (S3) = corneal apex superior at 1 mm (3 mm); I1 (I3) = corneal apex inferior at 1 mm (3 mm); N1 (N3) = corneal apex nasal at 1 mm (3 mm); T1 (T3) = corneal apex temporal at 1 mm (3 mm)