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Table 2 Intraoperator repeatability for epithelium thickness obtained using MS-39 in mild keratoconus patients

From: Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium

Parameter

Observer

Mean ± SD (μm)

Sw (μm)

TRT (μm)

CoV (%)

ICC (95% CI)

CET

1st

52.40 ± 4.81

0.78

2.17

1.49

0.974 (0.953 to 0.987)

 

2nd

52.59 ± 4.68

1.01

2.80

1.92

0.955 (0.920 to 0.976)

TET

1st

43.63 ± 2.85

1.76

4.89

4.04

0.695 (0.522 to 0.828)

 

2nd

44.11 ± 3.29

1.73

4.80

3.93

0.767 (0.624 to 0.870)

S1

1st

55.08 ± 4.18

1.26

3.49

2.29

0.914 (0.850 to 0.955)

 

2nd

54.65 ± 4.25

1.40

3.86

2.55

0.900 (0.827 to 0.946)

S3

1st

48.47 ± 4.17

1.87

5.18

3.86

0.823 (0.686 to 0.912)

 

2nd

48.41 ± 4.01

2.09

5.78

4.31

0.770 (0.627 to 0.874)

I1

1st

50.44 ± 4.33

1.12

3.09

2.21

0.936 (0.887 to 0.967)

 

2nd

50.58 ± 4.36

1.14

3.15

2.25

0.935 (0.886 to 0.966)

I3

1st

51.92 ± 4.44

1.80

4.98

3.46

0.852 (0.749 to 0.921)

 

2nd

51.82 ± 4.33

1.81

5.02

3.50

0.843 (0.737 to 0.915)

N1

1st

53.61 ± 5.41

0.96

2.66

1.79

0.969 (0.944 to 0.984)

 

2nd

54.82 ± 4.30

1.20

3.31

2.18

0.926 (0.871 to 0.961)

N3

1st

52.81 ± 4.12

1.43

3.95

2.70

0.889 (0.809 to 0.941)

 

2nd

53.47 ± 4.08

1.54

4.27

2.88

0.870 (0.780 to 0.930)

T1

1st

52.51 ± 4.23

0.98

2.72

1.87

0.948 (0.907 to 0.973)

 

2nd

51.34 ± 4.65

1.25

3.47

2.44

0.931 (0.879 to 0.964)

T3

1st

52.19 ± 3.69

1.55

4.28

2.96

0.843 (0.735 to 0.916)

 

2nd

51.80 ± 4.07

1.31

3.62

2.52

0.903 (0.833 to 0.949)

  1. SD = standard deviation; Sw = within-subject standard deviation; TRT = test-retest repeatability (2.77 Sw); CoV = coefficient of variation; ICC = intraclass correlation coefficient; CET = central epithelium thickness; TET = thinnest epithelium thickness; S1 (S3) = corneal apex superior at 1 mm (3 mm); I1 (I3) = corneal apex inferior at 1 mm (3 mm); N1 (N3) = corneal apex nasal at 1 mm (3 mm); T1 (T3) = corneal apex temporal at 1 mm (3 mm)