Parameters | Cases (n = 161) | Controls (n = 451) | P value |
---|---|---|---|
Gender, n (%) | Â | Â | 0.120 |
 Female | 101 (62.7%) | 251 (55.7%) |  |
 Male | 60 (37.3%) | 200 (44.3%) |  |
Age, mean (SD) | 74.8 (6.8) | 71.8 (6.4) | < 0.001 |
Smoking, n (%) | Â | Â | 0.600 |
 Non-smoker | 136 (84.5%) | 386 (86.0%) |  |
 Smoker/ex-smoker | 25 (15.5%) | 63 (14.0%) |  |
Obesity, n (%) | Â | Â | 0.140 |
 BMI < 25 kg/m2 | 47 (29.4%) | 106 (23.5%) |  |
 BMI ≥ 25 kg/m2 | 113 (70.6%) | 345 (76.5%) |  |
Educational status, n (%) | Â | Â | 0.200 |
 Basic education | 136 (84.5%) | 382 (84.7%) |  |
 High school | 10 (6.2%) | 36 (8.0%) |  |
 Higher education | 3 (1.9%) | 16 (3.5%) |  |
 Without education | 12 (7.5%) | 17 (3.8%) |  |
Physical exercise, n (%) | Â | Â | 0.008 |
 No | 104 (64.6%) | 237 (52.5%) |  |
 Yes | 57 (35.4%) | 214 (47.5%) |  |
Genetic risk score, n (%) |  |  | < 0.001 |
 Low GRS | 62 (38.5%) | 244 (54.1%) |  |
 High GRS | 99 (61.5%) | 207 (45.9%) |  |
mediSCORE, n (%) |  |  | < 0.001 |
 High | 15 (9.3%) | 105 (23.3%) |  |
 Low | 146 (90.7%) | 346 (76.7%) |  |
mediSCORE componentsa, n (%) | Â | Â | Â |
 Vegetables | 62 (38.5%) | 243 (53.9%) | < 0.001 |
 Legumes | 77 (47.8%) | 249 (55.2%) | 0.110 |
 Fruits | 59 (36.6%) | 250 (55.4%) | < 0.001 |
 Cereals | 90 (55.9%) | 225 (49.9%) | 0.200 |
 Fish | 90 (55.9%) | 221 (49.0%) | 0.130 |
 Dairy products | 98 (60.9%) | 214 (47.5%) | 0.003 |
 Meat | 87 (54.0%) | 233 (51.7%) | 0.600 |
 Alcohol | 14 (8.7%) | 36 (8.0%) | 0.800 |
 Ratio of monounsaturated lipids/saturated lipids | 71 (44.1%) | 214 (47.5%) | 0.500 |