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Table 3 Eight-year outcomes in visual field mean deviation, cup-to-disc ratio, retinal nerve fiber layer thickness, and ganglion cell-inner plexiform layer thickness

From: Long-term outcomes of two first-generation trabecular micro-bypass stents (iStent) with phacoemulsification in primary open-angle glaucoma: eight-year results

Variable

N

Mean

% Change vs. baseline

Mean change vs. baseline

P value

VF-MD (dB)

 Preoperative

58

− 5.9 ± 6.6

   

 POY1

52

− 4.1 ± 5.8

− 30.5

1.8

0.092

 POY2

46

− 4.7 ± 6.0

− 20.3

1.2

0.130

 POY3

47

− 6.3 ± 6.5

6.8

− 0.4

0.227

 POY4

46

− 5.8 ± 6.3

− 1.7

0.1

0.953

 POY5

45

− 5.5 ± 6.4

− 6.8

0.4

0.634

 POY6

44

− 7.0 ± 7.1

18.6

− 1.1

0.027*

 POY7

45

− 6.6 ± 7.3

11.9

− 0.7

0.043*

 POY8

57

− 8.0 ± 7.8

35.6

− 2.1

 < 0.001**

CDR

 Preoperative

42

0.71 ± 0.16

   

 POY1

45

0.71 ± 0.16

0.0

0.00

0.751

 POY2

52

0.70 ± 0.17

− 1.4

− 0.01

0.203

 POY3

49

0.70 ± 0.17

− 1.4

− 0.01

0.322

 POY4

48

0.70 ± 0.16

− 1.4

− 0.01

0.310

 POY5

48

0.70 ± 0.16

− 1.4

− 0.01

0.187

 POY6

47

0.71 ± 0.16

0.0

0.00

0.830

 POY7

45

0.71 ± 0.15

0.0

0.00

0.782

 POY8

53

0.70 ± 0.16

− 1.4

− 0.01

0.176

RNFL thickness (μm)

 Preoperative

14

70.5 ± 13.7

   

 POY1

19

71.7 ± 11.3

1.7

1.2

0.613

 POY2

35

74.4 ± 13.5

5.5

3.9

0.205

 POY3

36

74.7 ± 12.6

6.0

4.2

0.214

 POY4

39

74.8 ± 11.3

6.1

4.3

0.192

 POY5

42

74.7 ± 12.0

6.0

4.2

0.222

 POY6

41

74.6 ± 12.6

5.8

4.1

0.230

 POY7

40

75.2 ± 12.2

6.7

4.7

0.181

 POY8

49

74.3 ± 11.9

5.4

3.8

0.228

GC-IPL thickness (μm)

 Preoperative

14

64.4 ± 12.9

   

 POY1

19

65.7 ± 11.2

2.0

1.3

0.623

 POY2

34

65.6 ± 13.1

1.9

1.2

0.674

 POY3

36

64.2 ± 11.9

− 0.3

− 0.2

0.962

 POY4

39

67.4 ± 11.2

4.7

3.0

0.337

 POY5

42

65.5 ± 11.5

1.7

1.1

0.679

 POY6

41

64.2 ± 12.5

− 0.3

− 0.2

0.966

 POY7

40

65.1 ± 11.4

1.1

0.7

0.752

 POY8

48

63.8 ± 10.9

− 0.9

− 0.6

0.857

  1. VF-MD visual field mean deviation; CDR cup-to-disc ratio; RNFL retinal nerve fiber layer; GC-IPL ganglion cell-inner plexiform layer; POM postoperative month; POY postoperative year
  2. Mean ± Standard deviations are presented and statistically compared to preoperative values using Generalized Estimating Equations with sequential Bonferroni correction for multiple comparisons. Statistical significance is denoted by * for P < 0.05 and ** for P < 0.001