Long-term outcomes of two first-generation trabecular micro-bypass stents (iStent) with phacoemulsification in primary open-angle glaucoma: eight-year results

Table 2 Eight-year outcomes in intraocular pressure, glaucoma medication use, and best-corrected visual acuity

Variable	N	Mean	% Change vs. baseline	Mean change vs. baseline	P value
IOP (mmHg)
Preoperative	62	19.2 ± 3.9
POM1	62	15.4 ± 3.5	− 19.8	− 3.8	< 0.001**
POM6	57	15.5 ± 3.4	− 19.3	− 3.7	< 0.001**
POY1	59	15.8 ± 3.0	− 17.7	− 3.4	< 0.001**
POY2	57	15.7 ± 3.1	− 18.2	− 3.5	< 0.001**
POY3	54	15.7 ± 3.0	− 18.2	− 3.5	< 0.001**
POY4	53	14.9 ± 2.6	− 22.4	− 4.3	< 0.001**
POY5	53	14.6 ± 2.8	− 24.0	− 4.6	< 0.001**
POY6	51	14.8 ± 2.7	− 22.9	− 4.4	< 0.001**
POY7	56	14.9 ± 3.1	− 22.4	− 4.3	< 0.001**
POY8	56	14.2 ± 2.4	− 26.0	− 5.0	< 0.001**
Number of glaucoma medications
Preoperative	62	2.8 ± 1.1
POM1	62	0.9 ± 1.3	− 67.9	− 1.9	< 0.001**
POM6	58	1.2 ± 1.2	− 57.1	− 1.5	< 0.001**
POY1	58	1.3 ± 1.2	− 53.6	− 1.5	< 0.001**
POY2	57	1.5 ± 1.2	− 46.4	− 1.3	< 0.001**
POY3	55	1.6 ± 1.3	− 42.9	− 1.1	< 0.001**
POY4	55	1.9 ± 1.3	− 32.1	− 0.9	< 0.001**
POY5	55	2.1 ± 1.2	− 25.0	− 0.8	< 0.001**
POY6	56	2.2 ± 1.2	− 21.4	− 0.6	< 0.001**
POY7	56	2.3 ± 1.2	− 17.9	− 0.6	0.002*
POY8	56	2.3 ± 1.2	− 17.9	− 0.5	0.006*
BCVA (logMAR)
Preoperative	62	0.17 ± 0.15
POM1	62	0.11 ± 0.10	− 35.3	− 0.06	< 0.001**
POM6	57	0.10 ± 0.19	− 41.2	− 0.07	< 0.001**
POY1	56	0.09 ± 0.11	− 47.1	− 0.08	< 0.001**
POY2	58	0.07 ± 0.10	− 58.8	− 0.10	< 0.001**
POY3	53	0.07 ± 0.10	− 58.8	− 0.10	< 0.001**
POY4	52	0.08 ± 0.11	− 52.9	− 0.09	< 0.001**
POY5	53	0.06 ± 0.09	− 64.7	− 0.11	< 0.001**
POY6	51	0.09 ± 0.11	− 47.1	− 0.08	< 0.001**
POY7	55	0.12 ± 0.12	− 29.4	− 0.05	0.014*
POY8	56	0.11 ± 0.14	− 35.3	− 0.06	0.015*

Mean ± standard deviations are presented and statistically compared to preoperative values using Generalized Estimating Equations with sequential Bonferroni correction for multiple comparisons
IOP intraocular pressure; BCVA best-corrected visual acuity; POM postoperative month; POY postoperative year
Statistical significance is denoted by * for P < 0.05 and ** for P < 0.001

ISSN: 2326-0254