Table 3 Synthesis of previously reported findings regarding choroidal thickness in patients with Graves’ disease
From: Choroidal vascularity index in thyroid-associated ophthalmopathy: a cross-sectional study
Authors | Methods | Nationality of the study population | Results | Correlation with ocular parameters | Correlation with systemic parameters | Study limitations |
|---|---|---|---|---|---|---|
Cagiltay and Akay 2018 [9] | Subfoveal CT; at 500 μm, 1000 μm, and 1500 μm temporal and nasal to the fovea | Turkish | Increased subfoveal, mean and temporal CT; no difference in nasal CT | Correlation with VISA score No correlation with exophthalmometry, axial length | No correlation with disease duration, mean blood pressure | Superior or inferior CT not measured |
Bruscolini et al.2018 [10] | Subfoveal CT | Italian | Increased subfoveal CT | Correlation with CAS and exophthalmometry | No correlation with disease duration | Small sample size (n = 18); lack of perifoveal measurements |
Ă–zkan et al.2016 [11] | Subfoveal CT | Turkish | Increased subfoveal CT | Correlation with CAS and elongated VEP P100 | N/A | Only SFCT was examined; small sample size |
Lai et al. 2019 [12] | Subfoveal CT; at 1 mm and 2 mm nasal, temporal, inferior and superior to the fovea; peripapillary region | Chinese | Increased CT in all point except at 2 mm inferior to the fovea and at peripapillary region | Association with axial length, exophthalmometry and BCVA No association with IOP and CAS | No association with age, gender, duration of TAO, history of smoking | Most patients with CAS < 4 |
Yu and Zhang 2018 [13] | Subfoveal CT; at 1500 μm and 3000 μm nasal and temporal to the fovea | Chinese | CT increased in all points | No relationship with CAS, degree of exophthalmos | No relationship with T3, T4, TSH, TRAb levels | Lack of superior and inferior measurements |
Çalışkan et al. 2017 [14] | Subfoveal CT, at 1.5-mm and 3.0-mm nasal and temporal to the fovea | Turkish | Increased CT | Correlation with CAS, IOP | Correlation with age, disease activity | Wide range of patient age (21–65 years) |