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Table 1 Effects of SCH 23390, picrotoxin and combined picrotoxin + SCH 23390 application on the latency of the ERG b- and d-waves, obtained at different time periods (minutes from the beginning of the experiment)

From: Effects of dopamine D1 receptor blockade on the ERG b- and d-waves during blockade of ionotropic GABA receptors

Group

Latency (ms)

10 min

21 min

37 min

48 min

R

b-wave

115 ± 4.92

112 ± 6.58

111 ± 3.09

110 ± 5.20

d-wave

104 ± 5.05

100 ± 7.14

105 ± 8.54

97 ± 8.45

SCH

b-wave

113 ± 3.47

117 ± 5.28

  

d-wave

95 ± 6.66

106 ± 8.77

  

PT

b-wave

124 ± 7.36

 

135 ± 6.74

133 ± 7.21

   

p < 0.008

 

d-wave

104 ± 6.91

 

127 ± 7.60

127 ± 7.29

   

p < 0.00002

 

PT+SCH

b-wave

127 ± 5.21

 

133 ± 5.98

133 ± 7.05

   

p < 0.042

 

d-wave

112 ± 6.81

 

131 ± 7.60

127 ± 9.5

   

p < 0.018

 
  1. The statistical significance of the differences between the values obtained before (10 min) and after drug application (37 min) is evaluated using paired t-test. Means ± SEM are shown